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Article

PARP1 Gene Polymorphisms and the Prognosis of Esophageal Cancer Patients from Cixian High-Incidence Region in Northern China.

Asian Pacific journal of cancer prevention : APJCP - 1 Oct 2020

Zhou Rong-Miao, Li Yan, Wang Na, Niu Chao-Xu, Huang Xi, Cao Shi-Ru, Huo Xiang-Ran

Abstract excerpt

OBJECTIVE: Poly (ADP-ribose) polymerase 1 (PARP1), as a key enzyme in the base excision repair pathway, plays a crucial role in tumorigenesis and progression. This study aimed to assess whether polymorphisms of PARP1 gene could be used as predictive biomarkers for the survival of esophageal squamous cell carcinoma (ESCC) patients from Cixian high-incidence region in northern China. METHODS: In 203 ESCC patients...

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Identifiers

PMID: 33112558
DOI: 10.31557/APJCP.2020.21.10.2987
PMCID: PMC7798169

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