Article
ERCC1 single nucleotide polymorphism C8092A, but not its expression is associated with survival of esophageal squamous cell carcinoma patients from Fujian province, China.
PloS one - 1 Jan 2014
Chen Wan-Hua, Xin Pei-Ling, Pan Qun-Xiong, Chen Ya-Yun, Wang Cong-Ren, Zhang Zhi-Shan, Chen Yi-Feng, Zhang Chao-Yang, Cai Wen-Jie
Abstract excerpt
Esophageal carcinoma is one of the world's deadliest cancers. Esophageal squamous cell carcinoma (ESCC) is more frequent than adenocarcenoma (AC) in China. Platinum-based chemotherapy with surgical resection is a common treatment approach for ESCC; however, the treatment response is uncertain. Evidence suggests polymorphisms in genes encoding excision repair cross-complementing group 1 (ERCC1), a protein involved...
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