Article
DNA repair gene polymorphisms and clinical outcome of patients with primary small cell carcinoma of the esophagus.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2015
Zhou Qiang, Zou Bing-Wen, Xu Yong, Xue Jian-Xin, Meng Mao-Bin, Liu Fang-Jiu, Deng Lei, Ma Dai-Yuan, Ao Rui, Lu You
Abstract excerpt
Polymorphisms in DNA repair genes impact on the synthesis of DNA repair proteins that are crucial to the repair of DNA damages induced by chemotherapy and radiotherapy. We retrospectively examined whether there was an association between the selected six single nucleotide polymorphisms (SNPs) of five DNA repair genes (PARP1-Val762Ala, XRCC1-Arg194Trp, XRCC1-Arg399Gln, XPC-Lys939Gln, BRCA1-Lys1183Arg, and...
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