MDM4 polymorphisms associated with the risk but not the prognosis of esophageal cancer in Cixian high-incidence region from northern China.

doi:10.1111/ajco.13746

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Article

MDM4 polymorphisms associated with the risk but not the prognosis of esophageal cancer in Cixian high-incidence region from northern China.

Asia-Pacific journal of clinical oncology - 1 Oct 2022

Zhou Rongmiao, Li Yan, Wang Na, Niu Chaoxu, Huang Xi, Cao Shiru, Huo Xiangran

Abstract excerpt

AIM: The mouse double minute 4 (MDM4) may contribute to tumorgenesis by inhibiting p53 tumor suppressor activity. This study was designed to investigate whether MDM4 polymorphisms could affect susceptibility to esophageal squamous cell carcinoma (ESCC) and the survival of ESCC patients in a population from Cixian high-incidence region of northern China, which has not been explored. METHODS: MDM4 rs1380576 and...

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PMID: 35098683
DOI: 10.1111/ajco.13746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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