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Article

PARP1 polymorphisms increase the risk of gastric cancer in a Chinese population.

Molecular diagnosis & therapy - 1 Feb 2012

He Wenting, Liu Tao, Shan Yong, Zhu Kexiang, Li Yumin

Abstract excerpt

BACKGROUND AND OBJECTIVE: Poly(adenosine diphosphate [ADP]-ribose) polymerase 1 (PARP1), a protein involved in the DNA repair mechanism, plays an important role in carcinogenesis. In this study, we investigated whether single nucleotide polymorphisms of PARP1 contribute to gastric cancer (GC) and its precursor lesions (gastric precancerous lesions; GPL) in a case-control study conducted in the Hexi area of China,...

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Source

Identifiers

PMID: 22221038
DOI: 10.1007/BF03256428

Genes

PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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