Genetic variants in DNA repair predicts the survival of patients with esophageal cancer.

doi:10.1097/SLA.0b013e318216f374

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Article

Genetic variants in DNA repair predicts the survival of patients with esophageal cancer.

Annals of surgery - 1 May 2011

Lee Jang-Ming, Yang Pei-Wen, Yang Shi-Yi, Chuang Tzu-Hsuen, Tung En-Chi, Chen Jin-Shing, Huang Pei-Ming, Lee Yung-Chie

Abstract excerpt

OBJECTIVE: To investigate the association of the genetic variants in excision repair cross-complementation group 2 (ERCC2) R156R and ERCC4 rs3136038 with survival duration for patients with esophageal cancer. BACKGROUND: ERCC2 and ERCC4 are important molecules participating nucleotide excision repair system. The clinical relevance of the genetic variants of these genes is largely unknown currently. PATIENTS AND...

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Identifiers

PMID: 21490450
DOI: 10.1097/SLA.0b013e318216f374

Genes

ERCC2
ERCC4

Variants

rs3136038

Provenance

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