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Article

The impact of endotrophin on the progression of chronic liver disease.

Experimental & molecular medicine - 1 Oct 2020

Kim Min, Lee Changhu, Seo Dae Yun, Lee Hyojung, Horton Jay D, Park Jiyoung, Scherer Philipp E

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease and can lead to multiple complications, including non-alcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma. The fibrotic liver is characterized by the pathological accumulation of extracellular matrix (ECM) proteins. Type VI collagen alpha3 (Col6a3) is a biomarker of hepatic fibrosis, and its cleaved form, endotrophin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33110211
DOI: 10.1038/s12276-020-00520-8
PMCID: PMC8080612

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