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Article

Liver Fibrosis and Inflammation under the Control of ERK2.

International journal of molecular sciences - 27 May 2020

Jeng Kuo-Shyang, Lu Ssu-Jung, Wang Chih-Hsuan, Chang Chiung-Fang

Abstract excerpt

Chronic liver injury could lead the formation of liver fibrosis, eventually some would develop to hepatocellular carcinoma (HCC), one of the leading malignancies worldwide. The aim of the study is to dissect the role of extracellular signal-regulated kinase 2 (ERK2) signaling in liver fibrosis and inflammation. The choline-deficient, ethionine-supplemented (CDE) diet could lead to fatty livers and generate oval...

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PMID: 32471201
DOI: 10.3390/ijms21113796
PMCID: PMC7312875

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