Article

Hepatic Cholesteryl Ester Transfer Protein Regulates Sex-specific Liver Metabolic Adaptation and Metabolic-Associated Steatotic Liver Disease Risk in Diet-induced Obesity

2026-07-02

Abstract excerpt

Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) and associated dyslipidemia is a growing health issue that gives rise to cardiovascular risk. Men are more prone to development of MASLD than women. Understanding mechanisms underlying sex differences in MASLD may lead to improved prevention and treatment approaches. Cholesteryl ester transfer protein (CETP) is a lipid transfer protein that shuttles...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f524896d-6ad5-5dc8-8b59-f0cf1b199577
DOI: 10.64898/2026.06.28.735072

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hepatic Cholesteryl Ester Transfer Protein Regulates Sex-specific Liver Metabolic Adaptation and Metabolic-Associated Steatotic Liver Disease Risk in Diet-induced ObesityDOI 10.64898/2026.06.28.735072Read

Cholesteryl Ester Transfer Protein (CETP) Variations in Relation to Lipid Profiles and Cardiovascular Diseases: An Update.Semantic proximity Read

Sex- and age-associated factors drive the pathophysiology of MASLDSemantic proximity Read

Sex-specific lipid-mediated mechanisms drive MASLD progression revealed by paired liver–blood multi-omicsSemantic proximity Read

Metabolic alterations and hepatitis C: From bench to bedside.Semantic proximity Read

Non-alcoholic Fatty Liver Disease as a Canonical Example of Metabolic Inflammatory-Based Liver Disease Showing a Sex-Specific Prevalence: Relevance of Estrogen SignalingSemantic proximity Read

Hepatic loss of AATF attenuates MASH by suppressing AKT–mTORC1 signaling and reprogramming lipid metabolismSemantic proximity Read

WITHDRAWN: Endurance Training Alleviates Metabolic-associated Fatty-liver Disease (MAFLD)-related Testicular Impairments via ER Stress RegulationSemantic proximity Read

Low-density lipoprotein receptor is required for cholesteryl ester transfer protein to regulate triglyceride metabolism in both male and female mice.Semantic proximity Read

C/EBPβ transcription factor promotes alcohol-induced liver fibrosis in males via HDL remodelingSemantic proximity Read

The Role of Phosphatidylethanolamine N-Methyltransferase (PEMT) and Its Waist-Hip-Ratio-Associated Locus rs4646404 in Obesity-Related Metabolic Traits and Liver DiseaseSemantic proximity Read

Humanized diet and thermoneutral housing enable sex-aware dissection of the MASLD-T2D-CVD triadSemantic proximity Read

Chromosomal and gonadal sex drive sex differences in lipids and hepatic gene expression in response to hypercholesterolemia and statin treatmentSemantic proximity Read