Article
Local and Systemic Concentrations of Pattern Recognition Receptors of the Lectin Pathway of Complement in a Cohort of Patients With Interstitial Lung Diseases.
Frontiers in immunology - 1 Jan 2020
Vogt Severin, Trendelenburg Marten, Tamm Michael, Stolz Daiana, Hostettler Katrin Esther, Osthoff Michael
Abstract excerpt
Background: The role of the lectin pathway of complement in the pathogenesis of interstitial lung diseases (ILDs) is largely unknown. Pattern recognition receptors (PRR) of the lectin pathway are involved in the clearance of apoptotic cells either via activation of the complement system or as direct opsonins. As recent findings suggest a role of apoptosis in the development of pulmonary fibrosis, the influence of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.