Article
Mannose-binding lectin is present in the infected airway: a possible pulmonary defence mechanism.
Thorax - 1 Feb 2009
Fidler K J, Hilliard T N, Bush A, Johnson M, Geddes D M, Turner M W, Alton E W F W, Klein N J, Davies J C
Abstract excerpt
BACKGROUND: Mannose-binding lectin (MBL) deficiency has been associated with infections of the respiratory tract and with increased disease severity in cystic fibrosis (CF). The mechanism is uncertain, and could relate either to systemic or local effects. The aim of this study was to determine, in a large cohort of children, whether MBL is present on the airway surface in health or disease. METHODS:...
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