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JAK/STAT pathway and molecular mechanism in bone remodeling

24 Oct 2020

Abstract excerpt

JAK/STAT signaling pathway is involved in many diseases, including autoimmune diseases, which are characterized by a close interconnection between immune and bone system. JAK/STAT pathway is involved in bone homeostasis and plays an important role in proliferation and differentiation of some cell types, including osteoblasts and osteoclasts. Different molecules, such as cytokines, hormones, and growth factors are...

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PMID: 33099760
DOI: 10.1007/s11033-020-05910-9

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