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Article

Biology and significance of the JAK/STAT signalling pathways.

Growth factors (Chur, Switzerland) - 1 Apr 2012

Kiu Hiu, Nicholson Sandra E

Abstract excerpt

Since its discovery two decades ago, the activation of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway by numerous cytokines and growth factors has resulted in it becoming one of the most well-studied intracellular signalling networks. The field has progressed from the identification of the individual components to high-resolution crystal structures of both JAK and STAT, and...

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Identifiers

PMID: 22339650
DOI: 10.3109/08977194.2012.660936
PMCID: PMC3762697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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