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Article

The JAK/STAT Pathway in Skeletal Muscle Pathophysiology

30 Apr 2019

Abstract excerpt

The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway is a key intracellular mediator of a variety of metabolically relevant hormones and cytokines, including the interleukin-6 (IL-6) family of cytokines. The JAK/STAT pathway transmits extracellular signals to the nucleus, leading to the transcription of genes involved in multiple biological activities. The JAK/STAT pathway has...

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PMID: 31114509
DOI: 10.3389/fphys.2019.00500

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