Article
Significant Associations between AXIN1 rs1805105, rs12921862, rs370681 Haplotypes and Variant Genotypes of AXIN2 rs2240308 with Risk of Congenital Heart Defects.
International journal of environmental research and public health - 21 Oct 2020
Crauciuc George Andrei, Iancu Mihaela, Olah Peter, Tripon Florin, Anciuc Mădălina, Gozar Liliana, Togănel Rodica, Bănescu Claudia
Abstract excerpt
This study aimed to investigate possible associations of the susceptibility to congenital heart defects (CHDs) with AXIN1 rs1805105, rs12921862 and rs370681 gene variants and haplotypes, and AXIN2 rs2240308 gene variant. Significant associations were identified for AXIN1 rs370681 and AXIN2 variants. AXIN1 variant was significantly associated with decreased odds of CHDs (adjusted OR varying from...