Article
Clinical relevance of breast and gastric cancer-associated polymorphisms as potential susceptibility markers for oral clefts in the Brazilian population.
BMC medical genetics - 4 Apr 2017
Machado Renato Assis, de Freitas Edimilson Martins, de Aquino Sibele Nascimento, Martelli Daniella Reis B, Swerts Mário Sérgio Oliveira, Reis Silvia Regina de Almeida, Persuhn Darlene Camati, Moreira Helenara Salvati Bertolossi, Dias Verônica Oliveira, Coletta Ricardo D, Martelli-Júnior Hercílio
Abstract excerpt
BACKGROUND: Epidemiological studies have indicated a higher incidence of breast and gastric cancer in patients with nonsyndromic cleft lip with or without cleft palate (NSCL ± P) and their relatives, which can be based on similar genetic triggers segregated within family with NSCL ± P. METHODS: This multicenter study evaluated the association of 9 single nucleotide polymorphisms (SNP) in AXIN2 and CDH1,...
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