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Article

Congenital Heart Diseases: Genetic Risk Variants and Their Methylation Status.

Genes - 15 Nov 2022

Calzada-Dávila Melissa, Calvo-Anguiano Geovana, Martínez-de-Villarreal Laura E, Lugo-Trampe José J, González-Peña Sandra M, Ancer-Rodríguez Patricia R, Hernández-Almaguer María D, Campos-Acevedo Luis D

Abstract excerpt

(1) Background: The interaction between single nucleotide variants (SNVs) associated with congenital heart diseases (CHDs) and their gene methylation status has not been well researched. The aim of the present study was to determine if there is a relationship between the methy lation status (MS) of genes and the allelic variants associated with CHDs. (2) Methods: Seven SNVs of the genes AXIN1, TBX1, TBX20, and...

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PMID: 36421790
DOI: 10.3390/genes13112115
PMCID: PMC9690480

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