Article
Association between polymorphisms in AXIN1 gene and atrial septal defect.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Dec 2014
Pu Yan, Chen Peng, Zhou Bin, Wang Yanyun, Song Yaping, Peng Ying, Rao Li, Zhang Lin
Abstract excerpt
CONTEXT: AXIN1 is a central component of Wnt signalling pathway which is essential for embryonic development. OBJECTIVE: To investigate whether polymorphisms of AXIN1 contribute to ASD susceptibility. MATERIALS AND METHODS: Three tag SNPs (rs12921862, rs370681 and rs1805105) in AXIN1 were genotyped in 208 ASD patients and 302 healthy controls using polymerase chain reaction-restriction fragment length...
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