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Article

Association between congenital heart disease and NKX2.5 gene polymorphisms: systematic review and meta-analysis.

Biomarkers in medicine - 1 Dec 2020

González-Castro Thelma B, Tovilla-Zárate Carlos A, López-Narvaez María L, Juárez-Rojop Isela E, Calderón-Colmenero Juan, Sandoval Juan P, García-Montes José A, Blachman-Braun Ruben, Castillo-Avila Rosa G, García-Flores Esbeidy, Cazarín-Santos Benny G, Borgonio-Cuadra Verónica M, Posadas-Sánchez Rosalinda, Vargas-Alarcón Gilberto, Rodríguez-Pérez José M, Pérez-Hernández Nonanzit

Abstract excerpt

Aim: To analyze the association of NKX2.5 gene with congenital heart disease (CHD), and to determine if the variants rs703752, rs3729753 and rs2277923 increase the risk for developing CHD. Materials & methods: PubMed, EBSCO and Web of Science databases were screened to identify eligible studies. Through a comprehensive meta-analysis software, the association between NKX2.5 gene variants and susceptibility of CHD...

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Share to Alleles
Share to Databases, Genetic
Share to Gene Frequency
Share to Genetic Predisposition to Disease
Share to Heart Defects, Congenital
Share to Homeobox Protein Nkx-2.5
Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 33346701
DOI: 10.2217/bmm-2020-0190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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