Article
Distribution of HLA-DQ risk genotypes for celiac disease in Ethiopian children.
HLA - 1 Dec 2020
Gudeta Adugna N, Ramelius Anita, Balcha Taye T, Girma Alemayehu, Ilonen Jorma, Agardh Daniel
Abstract excerpt
Most patients with celiac disease are positive for either HLA-DQA1*05:01-DQB1*02 (DQ2.5) or DQA1*03:01-DQB1*03:02 (DQ8). Remaining few patients are usually DQA1*02:01-DQB1*02 (DQ2.2) carriers. Screenings of populations with high frequencies of these HLA-DQA1-DQB1 haplotypes report a 1% to 3% celiac disease prevalence. The aim was to determine the prevalence of HLA-DQ risk haplotypes for celiac disease in...
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