Article
Evaluation of HLA-DQ Genetic Risk Classes in Pediatric Cases for Celiac Disease: Role of HLA-DQ2 and DQ8 Haplotypes.
Indian pediatrics - 1 Aug 2026
Yilmaz Dagli Hatice, Artan Reha, Yılmaz Aygen
Abstract excerpt
OBJECTIVES: To determine the human leukocyte antigen (HLA)-DQ genotype pattern in children with celiac disease (CD). METHODS: We retrospectively reviewed 490 patients aged 2-18 years who presented to our clinic between 2014 and 2024 with suspected CD and underwent HLA-DQ tissue typing. RESULTS: Out of 490 patients, 220 were diagnosed as CD and 270 as controls. Analysis of CD samples for HLA types revealed that...
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