PNPLA3 polymorphisms are associated with raised alanine aminotransferase levels in hepatitis C virus genotype 3.

doi:10.1016/j.ajg.2020.09.002

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Article

PNPLA3 polymorphisms are associated with raised alanine aminotransferase levels in hepatitis C virus genotype 3.

Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology - 1 Dec 2020

Agrawal Tanvi, Gaggar Anuj, Subramanian Mani, Kottilil Shyam, Choudhary Abhijit, Rao Padaki N, Shah Sameer, Trehanpati Nirupma

Abstract excerpt

BACKGROUND AND STUDY AIMS: Hepatitis C virus (HCV) infection is one of the leading causes of end-stage liver diseases. This study aimed to determine the association between polymorphisms in interleukin 28B (IL28B), PNPLA3, toll-like receptor 7 (TLR7), nucleotide-binding oligomerization domain-containing protein 2 (NOD2) and retinoic inducible gene-I (RIG-I) and HCV genotype and clinical presentation in an Indian...

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PMID: 33071176
DOI: 10.1016/j.ajg.2020.09.002

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