Article
Impact of host IL28B rs12979860, rs8099917 in interferon responsiveness and advanced liver disease in chronic genotype 3 hepatitis C patients.
PloS one - 1 Jan 2014
Firdaus Rushna, Biswas Aritra, Saha Kallol, Mukherjee Anirban, Chaudhuri Sujit, Chandra Alok, Konar Asokananda, Sadhukhan Provash Chandra
Abstract excerpt
BACKGROUND AND AIMS: Genetic polymorphisms near interleukin 28B gene are associated with spontaneous and treatment induced clearance of hepatitis C virus (HCV). Our objective was to evaluate the impact of interleukin 28B single nucleotide polymorphism (rs12979860, rs8099917) variability in HCV genotype 3 infected populations. METHODS: 400 hepatitis C seroreactive patients from different population groups in...
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