Article
Promoter region polymorphism & expression profile of toll like receptor-3 (TLR-3) gene in chronic hepatitis C virus (HCV) patients from India.
The Indian journal of medical research - 1 Aug 2011
Medhi Subhash, Deka Manab, Deka Purabi, Swargiary Shyam S, Hazam Rajib K, Sharma Manash P, Gumma Phani K, Asim Mohammad, Kar P
Abstract excerpt
BACKGROUND & OBJECTIVES: Hepatitis C virus (HCV) induces an immune response of the host, manifested by the formation of anti-HCV antibodies mediated by adaptive and innate immunity. Toll-like receptors (TLRs) play a pivotal role in innate immunity system. This study was aimed to investigate the promoter region polymorphism and expression of TLR3 gene in patients with chronic HCV infection. METHODS: Patients with...
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