Article
HLA-A*31 as a marker of genetic susceptibility to sepsis.
Revista Brasileira de terapia intensiva - 1 Jan 2000
da Silva Fabiano Pinheiro, Preuhs Filho Germano, Finger Eduardo, Barbeiro Hermes Vieira, Zampieri Fernando Godinho, Goulart Alessandra Carvalho, Torggler Filho Francisco, Panajotopoulos Nicolas, Velasco Irineu Tadeu, Kalil Jorge, de Souza Heraldo Possolo, da Cruz Neto Luiz Monteiro, Rodrigues Hélcio
Abstract excerpt
OBJECTIVE: The HLA haplotype has been associated with many autoimmune diseases, but no associations have been described in sepsis. This study aims to investigate the HLA system as a possible marker of genetic sepsis susceptibility. METHODS: This is a prospective cohort study including patients admitted to an intensive care unit and healthy controls from a list of renal transplant donors. Patients with less 18...
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