Article
PNPLA3 and HLA-DQB1 polymorphisms are associated with hepatocellular carcinoma after hepatitis C virus eradication.
Journal of gastroenterology - 1 Dec 2020
Miki Daiki, Akita Tomoyuki, Kurisu Akemi, Kawaoka Tomokazu, Nakajima Tomoaki, Hige Shuhei, Karino Yoshiyasu, Toyoda Hidenori, Kumada Takashi, Tsuge Masataka, Hiramatsu Akira, Imamura Michio, Aikata Hiroshi, Hayes Clair Nelson, Honda Koichi, Seike Masataka, Akuta Norio, Kobayashi Mariko, Kumada Hiromitsu, Tanaka Junko, Chayama Kazuaki
Abstract excerpt
BACKGROUND: Even though both interferon (IFN)-based and direct-acting antiviral (DAA) therapies against hepatitis C virus (HCV) reduce the risk of hepatocellular carcinoma (HCC), post-sustained virological response (SVR) patients remain at elevated risk of HCC. METHODS: A total of 4620 patients who achieved SVR were enrolled in this retrospective cohort study. After excluding patients who had a history of HCC or...
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