Article
Impact of the PNPLA3 genotype on the risk of hepatocellular carcinoma after hepatitis C virus eradication.
Journal of medical virology - 1 Oct 2022
Ohta Azusa, Ogawa Eiichi, Murata Masayuki, Matsumoto Yuji, Yamasaki Sho, Ikezaki Hiroaki, Furusyo Norihiro
Abstract excerpt
Almost all chronic hepatitis C (CHC) patients can achieve sustained virological response (SVR) with direct-acting antivirals. However, the development of hepatocellular carcinoma (HCC), even after the achievement of SVR, continues to be a serious problem. The aim of this study was to assess the association between host genetic factors and de novo HCC after SVR. This single-center, retrospective study consisted of...
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