The impact of PNPLA3 and JAZF1 on hepatocellular carcinoma in non-viral hepatitis patients with type 2 diabetes mellitus.

doi:10.1007/s00535-015-1116-6

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Article

The impact of PNPLA3 and JAZF1 on hepatocellular carcinoma in non-viral hepatitis patients with type 2 diabetes mellitus.

Journal of gastroenterology - 1 Apr 2016

Ueyama Misuzu, Nishida Nao, Korenaga Masaaki, Korenaga Keiko, Kumagai Erina, Yanai Hidekatsu, Adachi Hiroki, Katsuyama Hisayuki, Moriyama Sumie, Hamasaki Hidetaka, Sako Akahito, Sugiyama Masaya, Aoki Yoshihiko, Imamura Masatoshi, Murata Kazumoto, Masaki Naohiko, Kawaguchi Takumi, Torimura Takuji, Hyogo Hideyuki, Aikata Hiroshi, Ito Kiyoaki, Sumida Yoshio, Kanazawa Akio, Watada Hirotaka, Okamoto Koji, Honda Kenjiro, Kon Kazuyoshi, Kanto Tatsuya, Mizokami Masashi, Watanabe Sumio

Abstract excerpt

BACKGROUND: Type 2 diabetes mellitus (T2DM) is an established independent risk factor for hepatocellular carcinoma (HCC). T2DM is associated with non-alcoholic steatohepatitis (NASH), which is a major cause of non-HBV and non-HCV-related HCC; nevertheless, it has been difficult to identify those patients with T2DM who have a high risk of developing HCC. The aim of this study was to identify genetic determinants...

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Identifiers

PMID: 26337813
DOI: 10.1007/s00535-015-1116-6

Genes

PNPLA3
JAZF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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