Article
Clinicopathological Characteristics of PIK3CA Mutation and Amplification in Korean Patients with Breast Cancers.
International journal of medical sciences - 1 Jan 2020
Lee Moo-Hyun, Cho Ji-Hyung, Kwon Sun-Young, Jung Soo-Jung, Lee Jae-Ho
Abstract excerpt
The frequency of PIK3CA mutation and amplification was various and their clinical significances have not been clarified in Korean patients with invasive breast carcinoma (IBC). The study aimed to investigate the clinical and prognostic significances of PIK3CA mutation and amplification in IBC patients. DNA was isolated from paired normal and tumoral tissues in 128 IBC patients and the mutation and expression of...
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