Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence and Prognostic Role of PIK3CA/AKT1 Mutations in Chinese Breast Cancer Patients.

Cancer research and treatment - 1 Jan 2019

Deng Ling, Zhu Xuehua, Sun Yun, Wang Jiemin, Zhong Xiaorong, Li Jiayuan, Hu Min, Zheng Hong

Abstract excerpt

PURPOSE: The prevalence of PIK3CA in Chinese breast cancer patients may be underestimated. Therefore, we investigated the distribution of somatic PIK3CA/AKT1 mutations in Chinese breast cancer patients and explored their roles in tumor phenotypes and disease prognosis. MATERIALS AND METHODS: Tumors from 507 breast cancer patients were prospectively collected from the West China Hospital between 2008 and 2013....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Class I Phosphatidylinositol 3-Kinases
Share to Exome Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Proto-Oncogene Proteins c-akt

Share to Receptor, ErbB-2

Share to Receptors, Estrogen

Share to Receptors, Progesterone

Share to Survival Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 29540052
DOI: 10.4143/crt.2017.598
PMCID: PMC6333988

Genes

AKT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence and Prognostic Role of PIK3CA/AKT1 Mutations in Chinese Breast Cancer Patients.PMID 29540052Read ↗

Prevalence and spectrum of AKT1, PIK3CA, PTEN and TP53 somatic mutations in Chinese breast cancer patientsSemantic proximity Read ↗

Mutational Landscape of PI3K-AKT-mTOR Pathway in Breast Cancer: Implications for Targeted TherapeuticsSemantic proximity Read ↗

Clinicopathogenomic analysis of AKT1-PIK3CA-PTEN-altered luminal metastatic breast cancer in JapanSemantic proximity Read ↗

Correlation between activation of PI3K/AKT/mTOR pathway and prognosis of breast cancer in Chinese women.Semantic proximity Read ↗

Integrated analysis of promoter mutation, methylation and expression of AKT1 gene in Chinese breast cancer patients.Semantic proximity Read ↗

PIK3CA somatic alterations in invasive breast cancers: different spectrum from Caucasians to Chinese detected by next generation sequencing.Semantic proximity Read ↗

Evaluation of PIK3CA mutations as a biomarker in Chinese breast carcinomas from Western China.Semantic proximity Read ↗

Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients.Semantic proximity Read ↗

Analysis of PIK3CA Mutations with Clinicopathological Features and Prognosis in Breast cancer patients with Undergoing Neoadjuvant TherapySemantic proximity Read ↗

Clinical-Pathologic Analysis of Breast Cancer With PIK3CA Mutations in Chinese Women.Semantic proximity Read ↗

Mutational landscape of pan-cancer patients with PIK3CA alterations in Chinese population.Semantic proximity Read ↗

Clinicopathological Characteristics of PIK3CA Mutation and Amplification in Korean Patients with Breast Cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.