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Article

Role of a genetic variation in the microRNA-4421 binding site of ERP29 regarding risk of oropharynx cancer and prognosis.

Scientific reports - 12 Oct 2020

Carron Juliana, Costa Ana Paula Dalla, Rinck-Junior José Augusto, Mariano Fernanda Viviane, de Sá Carvalho Benilton, Lima Carmen Silvia Passos, Lourenço Gustavo Jacob

Abstract excerpt

We conducted a two-stage association study on patients with oropharynx (OP) squamous cell carcinoma (SCC) and healthy controls to identify single nucleotide variants (SNVs) located at the microRNA (miR)-binding sites of carcinogenesis genes associated with risk and prognosis of the disease. In stage 1, 49 patients and 49 controls were analyzed using Genome-Wide Human SNV Arrays to identify variants in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33046743
DOI: 10.1038/s41598-020-73675-z
PMCID: PMC7550560

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