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Article

Genetic susceptibility to esophageal cancer: the role of the nucleotide excision repair pathway.

Carcinogenesis - 1 May 2009

Pan Jennifer, Lin Jie, Izzo Julie G, Liu Yang, Xing Jinliang, Huang Maosheng, Ajani Jaffer A, Wu Xifeng

Abstract excerpt

In this case-control study with 387 White esophageal patients and 462 White controls matched to cases by age and sex, we evaluated the associations between 13 potential functional polymorphisms in eight major nucleotide excision repair (NER) genes and esophageal cancer risk. In individual single nucleotide polymorphism analysis, after adjustment for multiple comparisons, the heterozygous GT genotype of the ERCC1...

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Identifiers

PMID: 19270000
DOI: 10.1093/carcin/bgp058
PMCID: PMC2675653

Genes

ERCC1
XPA
XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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