Article
Pri-miR-124 rs531564 and pri-miR-34b/c rs4938723 polymorphisms are associated with decreased risk of esophageal squamous cell carcinoma in Chinese populations.
PloS one - 1 Jan 2014
Zhang Junjie, Huang Xuewen, Xiao Juanjuan, Yang Yajun, Zhou Yinghui, Wang Xiaofeng, Liu Qingmei, Yang Jingmin, Wang Mengyun, Qiu Lixin, Zheng Yabiao, Zhang Ping, Li Jin, Wang Ya'nong, Wei Qingyi, Jin Li, Wang Jiucun, Wang Minghua
Abstract excerpt
MicroRNAs are a new class of small non-protein-coding RNAs that sometimes function as tumor suppressors or oncogenes. Aberrant expression and structural alteration of microRNAs have been reported to be involved in tumorigenesis and cancer development. Recently, rs531564/pri-miR-124-1, rs4938723/pri-miR-34b/c, rs7372209/pri-miR-26a-1, rs895819/pre-miR-27a, and rs11134527/pri-miR-218 were reported to be associated...