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Short Communication: Genetic Variation in Human IL10 Proximal Promoter and Susceptibility to HIV-1 Infection in Mali, West Africa.

AIDS research and human retroviruses - 1 Jan 2021

Dabitao Djeneba, Dembele Mamadou, Urbanowski Michael, Kone Bourahima, Wague Mamadou, Coulibaly Nadie, Sarro Yeya Dit Sadio, Baya Bocar, Goita Drissa, Dao Sounkalo, Belson Michael, Klein Sabra L, Achenbach Chad, Holl Jane L, Diakite Mahamadou, Doumbia Seydou, Bream Jay H, Bishai William R, Diallo Souleymane, Murphy Robert L

Abstract excerpt

It is now recognized that to fully understand the role of host genetic variation on susceptibility to HIV-1 infection, investigations must be extended to African populations. We sought to determine if genetic variation in IL10 are associated with HIV-1 infection in a West African cohort in Mali. HIV-infected and -uninfected individuals were genotyped for three common single nucleotide polymorphisms (SNPs) located...

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Identifiers

PMID: 33045845
DOI: 10.1089/AID.2020.0140
PMCID: PMC7864090

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