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Article

Interleukin-10 (IL-10) pathway: genetic variants and outcomes of HIV-1 infection in African American adolescents.

PloS one - 14 Oct 2010

Shrestha Sadeep, Wiener Howard W, Aissani Brahim, Song Wei, Shendre Aditi, Wilson Craig M, Kaslow Richard A, Tang Jianming

Abstract excerpt

BACKGROUND: Immunological and clinical outcomes can vary considerably at the individual and population levels during both treated and untreated HIV-1 infection. Cytokines encoded by the interleukin-10 gene (IL10) family have broad immunomodulatory function in viral persistence, and several SNPs in the IL10 promoter sequence have been reported to influence pathogenesis or acquisition of HIV-1 infection....

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Identifiers

PMID: 20976276
DOI: 10.1371/journal.pone.0013384
PMCID: PMC2954785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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