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Article

Comparison of tyrosine kinase domain properties for the neurotrophin receptors TrkA and TrkB.

The Biochemical journal - 30 Oct 2020

Artim Stephen C, Kiyatkin Anatoly, Lemmon Mark A

Abstract excerpt

The tropomyosin-related kinase (Trk) family consists of three receptor tyrosine kinases (RTKs) called TrkA, TrkB, and TrkC. These RTKs are regulated by the neurotrophins, a class of secreted growth factors responsible for the development and function of neurons. The Trks share a high degree of homology and utilize overlapping signaling pathways, yet their signaling is associated with starkly different outcomes in...

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Identifiers

PMID: 33043964
DOI: 10.1042/BCJ20200695
PMCID: PMC7606831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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