Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Maternal High Fat Diet and Diabetes Disrupts Transcriptomic Pathways That Regulate Cardiac Metabolism and Cell Fate in Newborn Rat Hearts

17 Sept 2020

Abstract excerpt

Background: Children born to diabetic or obese mothers have a higher risk of heart disease at birth and later in life. Using chromatin immunoprecipitation sequencing, we previously demonstrated that late-gestation diabetes, maternal high fat (HF) diet, and the combination causes distinct fuel-mediated epigenetic reprogramming of rat cardiac tissue during fetal cardiogenesis. The objective of the present study was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Gestational Diabetes Research and Management
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33042024
DOI: 10.3389/fendo.2020.570846

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Maternal High Fat Diet and Diabetes Disrupts Transcriptomic Pathways That Regulate Cardiac Metabolism and Cell Fate in Newborn Rat HeartsPMID 33042024Read ↗

Maternal High Fat Diet and Diabetes Disrupts Transcriptomic Pathways that Regulate Cardiac Metabolism and Cell Fate in Newborn Rat HeartsSemantic proximity Read ↗

Prenatal Exposure to a Maternal High-Fat Diet Affects Histone Modification of Cardiometabolic Genes in Newborn Rats.Semantic proximity Read ↗

Role of Maternal Obesity in Offspring Cardiovascular Development and Congenital Heart DefectsSemantic proximity Read ↗

Research Progress of Maternal Metabolism on Cardiac Development and Function in OffspringSemantic proximity Read ↗

Diabetic Pregnancy and Maternal High-Fat Diet Impair Mitochondrial Dynamism in the Developing Fetal Rat Heart by Sex-Specific MechanismsSemantic proximity Read ↗

Maternal obesity causes fetal cardiac hypertrophy and alters adult offspring myocardial metabolism in miceSemantic proximity Read ↗

Adverse effects of Hif1a mutation and maternal diabetes on the offspring heart.Semantic proximity Read ↗

Sex-Dependent Epigenomic and Transcriptomic Reprogramming Links Maternal Obesity to Cardiac Remodeling in Adult OffspringSemantic proximity Read ↗

Insulin signaling and mitochondrial phenotype of skeletal muscle are programmed in utero by maternal diabetes.Semantic proximity Read ↗

Mitochondrial Transfer Improves Cardiomyocyte Bioenergetics and Viability in Male Rats Exposed to Pregestational DiabetesSemantic proximity Read ↗

The programming of cardiac hypertrophy in the offspring by maternal obesity is associated with hyperinsulinemia, AKT, ERK, and mTOR activation.Semantic proximity Read ↗

ER stress and lipid imbalance drive diabetic embryonic cardiomyopathy in an organoid model of human heart developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.