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Article

Downstream Sequences Control the Processing of the Pestivirus Erns-E1 Precursor.

Journal of virology - 9 Dec 2020

Mu Yu, Bintintan Ioana, Meyers Gregor

Abstract excerpt

Like other enveloped viruses, pestiviruses employ cellular proteases for processing of their structural proteins. While typical signal peptidase cleavage motifs are present at the carboxy terminus of the signal sequence preceding Erns and the E1/E2 and E2/P7 sites, the Erns-E1 precursor is cleaved by signal peptidase at a highly unusual structure, in which the transmembrane sequence upstream of the cleavage site...

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Identifiers

PMID: 33028718
DOI: 10.1128/JVI.01905-20
PMCID: PMC7737733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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