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Article

Age- and Phenotype-Dependent Changes in Circulating MMP-2 and MMP-9 Activities in Normotensive and Hypertensive Rats.

International journal of molecular sciences - 2 Oct 2020

Kollarova Marta, Puzserova Angelika, Balis Peter, Radosinska Dominika, Tothova Lubomira, Bartekova Monika, Barancik Miroslav, Radosinska Jana

Abstract excerpt

Matrix metalloproteinases (MMPs) are important in the pathogenesis of numerous diseases. The present study aimed to monitor the activation of MMP-2 and MMP-9 in spontaneously hypertensive rats (SHR) and their normotensive counterparts-Wistar-Kyoto rats (WKY). The animals were divided according to age (7, 20, and 52 weeks) and phenotype into: WKY-7, WKY-20, WKY-52, SHR-7, SHR-20 and SHR-52 groups. MMP plasma...

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Identifiers

PMID: 33023122
DOI: 10.3390/ijms21197286
PMCID: PMC7582756

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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