Article
Matrix metalloproteinases and atherogenesis in dependence of age.
Gerontology - 1 Jan 2007
Kunz Jochen
Abstract excerpt
BACKGROUND: Changes in the proteoglycan metabolism of the intima of arteries belong to the initial lesions of atherosclerosis (AS). The accumulation of proteoglycans, alterations of pericellular glycoproteins and modulations of collagen turnover also play a fundamental role in the progression of AS. They influence lipid retention, cell behavior and calcinosis. The decisive role played by the matrix...
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