Article
Matrix metalloproteinase 9 gene haplotypes affect left ventricular hypertrophy in hypertensive patients.
Clinica chimica acta; international journal of clinical chemistry - 14 Dec 2010
Lacchini Riccardo, Jacob-Ferreira Anna L B, Luizon Marcelo R, Coeli Fernanda B, Izidoro-Toledo Tatiane C, Gasparini Sandra, Ferreira-Sae Maria C, Schreiber Roberto, Nadruz Wilson, Tanus-Santos Jose E
Abstract excerpt
BACKGROUND: Matrix metalloproteinases (MMPs) are involved in cardiac remodeling and are encoded by genes showing genetic polymorphisms that have functional implications. We examined whether MMP-9 genetic polymorphisms are associated with hypertension and with left ventricular (LV) remodeling in hypertensive patients. METHODS: We studied 173 hypertensive patients and 137 age, race and gender matched healthy...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.