Article
Mouse genetic and phenotypic resources for human genetics.
Human mutation - 1 May 2012
Schofield Paul N, Hoehndorf Robert, Gkoutos Georgios V
Abstract excerpt
The use of model organisms to provide information on gene function has proved to be a powerful approach to our understanding of both human disease and fundamental mammalian biology. Large-scale community projects using mice, based on forward and reverse genetics, and now the pan-genomic phenotyping efforts of the International Mouse Phenotyping Consortium, are generating resources on an unprecedented scale, which...
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