Article
Genetic analysis in the Collaborative Cross breeding population.
Genome research - 1 Aug 2011
Philip Vivek M, Sokoloff Greta, Ackert-Bicknell Cheryl L, Striz Martin, Branstetter Lisa, Beckmann Melissa A, Spence Jason S, Jackson Barbara L, Galloway Leslie D, Barker Paul, Wymore Ann M, Hunsicker Patricia R, Durtschi David C, Shaw Ginger S, Shinpock Sarah, Manly Kenneth F, Miller Darla R, Donohue Kevin D, Culiat Cymbeline T, Churchill Gary A, Lariviere William R, Palmer Abraham A, O'Hara Bruce F, Voy Brynn H, Chesler Elissa J
Abstract excerpt
Genetic reference populations in model organisms are critical resources for systems genetic analysis of disease related phenotypes. The breeding history of these inbred panels may influence detectable allelic and phenotypic diversity. The existing panel of common inbred strains reflects historical selection biases, and existing recombinant inbred panels have low allelic diversity. All such populations may be...
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