Article
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2008
Chesler Elissa J, Miller Darla R, Branstetter Lisa R, Galloway Leslie D, Jackson Barbara L, Philip Vivek M, Voy Brynn H, Culiat Cymbeline T, Threadgill David W, Williams Robert W, Churchill Gary A, Johnson Dabney K, Manly Kenneth F
Abstract excerpt
Complex traits and disease comorbidity in humans and in model organisms are the result of naturally occurring polymorphisms that interact with each other and with the environment. To ensure the availability of resources needed to investigate biomolecular networks and systems-level phenotypes underlying complex traits, we have initiated breeding of a new genetic reference population of mice, the Collaborative...
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