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[Noncoding Polymorphism rs6832151 Is an Attractive Candidate for Genome Editing Aimed at Finding New Molecular Mechanisms of Autoimmune Diseases].

Molekuliarnaia biologiia - 1 Jan 2000

Ustiugova A S, Afanasyeva M A

Abstract excerpt

Currently only a small fraction of the proteins encoded in the human genome serve as pharmaceutical targets. Genome-wide association studies are a powerful tool to uncover new genetic loci responsible for predisposition to complex diseases, such as autoimmune disorders. However, further work is still required to identify causative single-nucleotide polymorphisms (SNPs) which directly mediate the disease risk at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33009792
DOI: 10.31857/S0026898420040175

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