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Article

Expression of long non-coding RNAs in autoimmunity and linkage to enhancer function and autoimmune disease risk genetic variants.

Journal of autoimmunity - 1 Jul 2017

Aune T M, Crooke P S, Patrick A E, Tossberg J T, Olsen N J, Spurlock C F

Abstract excerpt

Genome-wide association studies have identified numerous genetic variants conferring autoimmune disease risk. Most of these genetic variants lie outside protein-coding genes hampering mechanistic explorations. Numerous mRNAs are also differentially expressed in autoimmune disease but their regulation is also unclear. The majority of the human genome is transcribed yet its biologic significance is incompletely...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28420548
DOI: 10.1016/j.jaut.2017.03.014
PMCID: PMC5508524

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