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TERT Promoter Mutation in Serum Cell-Free DNA Is a Diagnostic Marker of Primary Hepatocellular Carcinoma in Patients with Nonalcoholic Fatty Liver Disease.

Oncology - 1 Jan 2021

Akuta Norio, Kawamura Yusuke, Kobayashi Mariko, Arase Yasuji, Saitoh Satoshi, Fujiyama Shunichiro, Sezaki Hitomi, Hosaka Tetsuya, Kobayashi Masahiro, Suzuki Yoshiyuki, Suzuki Fumitaka, Ikeda Kenji, Kumada Hiromitsu

Abstract excerpt

INTRODUCTION: It remains unclear whether TERT promoter mutation (TERT C228T) in serum cell-free DNA (cfDNA) is useful for the diagnosis of hepatocellular carcinoma (HCC) in patients with nonalcoholic fatty liver disease (NAFLD). METHODS: In this retrospective study, we analyzed the relationships between TERT C228T in serum cfDNA and levels of AFP and PIVKAII in 57 Japanese patients with histopathologically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32998139
DOI: 10.1159/000510366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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