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Article

Clinical significance of combined circulating TERT promoter mutations and miR-122 expression for screening HBV-related hepatocellular carcinoma.

Scientific reports - 18 May 2020

Trung Ngo Tat, Hoan Nghiem Xuan, Trung Pham Quang, Binh Mai Thanh, Van Tong Hoang, Toan Nguyen Linh, Bang Mai Hong, Song Le Huu

Abstract excerpt

Telomerase reverse-transcriptase (TERT) gene promoter mutations in circulating cell-free DNA (cfDNA) as well as the levels of circulating microRNA-122 (miR-122) have been reported as potential noninvasive biomarkers for several. This study evaluates the diagnostic performance of potent biomarker-based panels composing of serological AFP, miR-122 and circulating TERT promoter mutations for screening HBV-related...

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Share to Aged, 80 and over
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Hepatitis B virus

Share to Liver Neoplasms

Share to MicroRNAs

Share to Promoter Regions, Genetic

Share to Telomerase

Source

Open in PubMed Open full text

Identifiers

PMID: 32424223
DOI: 10.1038/s41598-020-65213-8
PMCID: PMC7234991

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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