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Article

Serum TERT C228T is an important predictor of non-viral liver cancer with fatty liver disease.

Hepatology international - 1 Apr 2022

Akuta Norio, Kawamura Yusuke, Suzuki Fumitaka, Kobayashi Mariko, Arase Yasuji, Saitoh Satoshi, Muraishi Nozomu, Fujiyama Shunichiro, Sezaki Hitomi, Hosaka Tetsuya, Kobayashi Masahiro, Suzuki Yoshiyuki, Ikeda Kenji, Kumada Hiromitsu

Abstract excerpt

BACKGROUND: Molecular therapies and precision medicine are expected to be developed for liver cancer based on the diagnosis of DNA somatic alterations. However, it remains unclear whether TERT promoter mutation (TERT C228T) in serum cfDNA is useful for the diagnosis of liver cancer with non-viral fatty liver disease (FLD). METHODS: This retrospective cohort study examined 258 Japanese patients who had a confirmed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35306637
DOI: 10.1007/s12072-022-10313-y
PMCID: PMC9013341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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