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Article

Straightforward protocol for allele-specific chromatin conformation capture.

Gene - 30 Jan 2021

Acemel R D, Tena J J, Gomez-Skarmeta J L, Fibla J, Royo J L

Abstract excerpt

A key advance in our understanding of gene regulation came with the finding that the genome undergoes three-dimensional nuclear folding in a genetically determined process. This 3D conformation directly influences the association between enhancers and their target promoters. This complex interplay has been proven to be essential for gene regulation, and genetic variants affecting this process have been associated...

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Share to Chromatin
Share to Databases, Genetic
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enhancer Elements, Genetic

Share to Nucleic Acid Conformation

Share to Promoter Regions, Genetic

Share to Quantitative Trait Loci

Share to Receptors, Cell Surface

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Identifiers

PMID: 32998049
DOI: 10.1016/j.gene.2020.145185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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